THE STUDY OF ESTABLISHMENT OF AN IN VIVO TUMOR MODEL BY THREE-DIMENSIONAL CELLS CULTURE SYSTEMS METHODS AND EVALUATION OF ANTITUMOR EFFECT OF BIOTIN-CONJUGATED PULLULAN ACETATE NANOPARTICLES

The study of establishment of an in vivo tumor model by three-dimensional cells culture systems methods and evaluation of antitumor effect of biotin-conjugated pullulan acetate nanoparticles

In this study, three-dimensional (3D) hydrogels were used for human hepatocellular carcinoma (HepG2) cells culture systems in vitro and establishment of an in vivo xenografted tumor model.Based on our previous work on the biotin-conjugated pullulan acetate nanoparticles (Bio-PA NPs) as anticancer drug carriers, we further studied the anti-tumor eff

read more